MLB matchup analysis

Twins vs Giants Prediction, Odds and Model Pick

Wednesday, September 23, 2026 at Oracle Park · 3:45 PM ET

Pass

Leo decision: Pass on Twins vs Giants

Lab Rating
3.1/10
Model lean
Twins 61.4%
Market probability
59.1%
Model edge
+2.3%
Best moneyline
-152
Sportsbooks checked
9
Leo model
61.4%
Market
59.1%

The case for Minnesota Twins

Late-inning bullpen advantage
San Francisco Giants relievers have a 5.56 ERA over the last 7 days; Minnesota Twins relievers have a 2.42. If this is still close after six innings, that gap favors Minnesota Twins.

The case for San Francisco Giants

The case is thin
The model finds little going San Francisco Giants's way — it trails on the pitching plan, bullpen, and recent form. The main path to a San Francisco Giants win is variance.

Why it is not official

Setup quality below the bar
Lab Rating is 3.1/10, under the 7.2/10 required for an official pick.
Cold stretch at the plate
Minnesota Twins is -0.041 wOBA below its own season form.

Why the setup score is what it is

Conviction: 3.18/10
Leo leans toward Minnesota Twins, but not strongly enough to earn full conviction credit.
Pitching plan: 12/40
Connor Prielipp rates 59 on Leo's pitcher score, judged on its own merits (50-80 is the credited range). Average or below by that measure, so it earns little or none of the available credit here -- independent of who the opponent is throwing.
Offense: 15.98/50
Minnesota Twins's recent form does not clearly outpace San Francisco Giants's.

Why the price is what it is

Team strength: 44.0%
Before any pitcher or bullpen adjustment, Leo's team-strength model alone makes Minnesota Twins 44.0% to win. Everything below moves the price from this starting point.
Pitcher score gap: 4 points
The pitcher-score gap favors Minnesota Twins by 4 points. This is the biggest single mover of the price -- a large gap moves it a lot, a small gap barely moves it.
Bullpen adjustment: +0.072
The bullpen-fatigue gap between the two pens nudges the price toward Minnesota Twins. This moves the price less than the starting pitchers do, since a starter covers more of the game than the bullpen.
Net effect: 44.0% -> 61.4%
Team strength alone had Minnesota Twins at 44.0%. After the pitcher and bullpen terms, the price is 61.4% -- the same number shown as Model Lean above.
The verdict Leo passes. The combined Lab Rating did not clear the official threshold.
Read the full model output

The combined Lab Rating did not clear the official threshold.

Final result

Twins 4, Giants 2

How the analysis held up

Minnesota Twins won, the side Leo's model favored.

Cesar Perdomo (No clear pitching-plan edge), the starter Leo's pitcher score favored, actually outpitched Connor Prielipp: 5.1 IP, 2 ER (3.38 ERA) against 5.1 IP, 2 ER (3.38 ERA). The edge held up.

The Minnesota Twins bullpen was not flagged pregame, but it had a night worth noting: 0 earned runs allowed over 3.2 relief innings (0.00 ERA) — quietly better than the pregame read implied.

The San Francisco Giants bullpen was flagged as elevated risk pregame (Tired). In relief it actually allowed 2 earned runs over 3.2 innings (4.91 ERA) — the risk read showed up.

San Francisco Giants scored 2, 1.5 fewer than the 3.5 pregame projection.

Game information

MatchupMinnesota Twins at San Francisco Giants
DateWednesday, September 23, 2026
First pitch3:45 PM ET
VenueOracle Park
Starting pitchersConnor Prielipp vs Cesar Perdomo
WeatherGame-time forecast: 78°F, 0% precipitation chance, 11 mph wind from W.

Starting pitcher matchup

Full Pitcher Matchup Tool →
Connor PrielippTwins · LHP
vs
Cesar PerdomoGiants · LHP
MetricTwinsGiants
Pitching planTraditional starterTraditional starter
Expected innings5⅓5⅓
ThrowsLL
Leo pitcher score (higher is better)5958
ERA (lower is better)4.873.65
WHIP (lower is better)1.291.38
K/9 (higher is better)9.25.1
K-BB% (higher is better)15.7%6.7%
K% (higher is better)23.9%13.5%
BB% (lower is better)8.2%6.7%
BB/9 (lower is better)3.22.6
HR/9 (lower is better)1.01.5
Ground-ball rate46.8%48.2%
Fly-ball rate53.2%51.8%

Pitcher edge: Leo gives Connor Prielipp a 1-point edge over Cesar Perdomo, driven mainly by K/9 (9.2 vs 5.1) and K-BB% (15.7% vs 6.7%).

How to read this: the scorecards above name the starters; every number lives in this table.

Strikeout Projections Full strikeout projections →

Connor Prielipp strikeouts
7.5 Leo projected Ks
Official pick: OVER 5.5K · +2.7K difference
Market 5.5K · O +112 / U -130 · 6 books
Cesar Perdomo strikeouts
3.1 Leo projected Ks
No K play · -0.4K difference is below Leo's 0.7K threshold
Market 3.5K · O -102 / U -123 · 6 books

Same data source as the Pitcher Matchup Tool, where every starter on the slate is compared side by side.

Twins are 4-6 in their last 10 and averaging 3.4 runs per game over the last 15 days; Giants are 3-7 in their last 10 and averaging 4.2 runs per game over the last 15 days. Season run differential separates them by almost nothing (-0.40 against -0.53).

MetricTwinsGiants
Last 104-63-7
Last 10 by venue (away team on the road, home team at home)5-5 on the road5-5 at home
OPS, last 15 days0.6260.678
wOBA, last 15 days (hot/cold read)0.2760.303
Runs per game, last 15 days3.44.2
K% last 15 days (lower is better)23.4%27.0%

Last 15 days only. Hot and cold streaks for all 30 teams live on the Stats page.

30-day offense

Full offense tool →
Last 30 daysTwinsGiants
OPS0.693 (-0.025 vs szn)0.718 (+0.007 vs szn)
Runs per game4.32 (-0.213 vs szn)4.90 (+0.714 vs szn)
wOBA (model offense input)0.306 (-0.011 vs szn)0.318
K% (lower is better)21.0%24.1% (+2.3% vs szn)

Over the last 30 days the Giants have been the better offense, 0.318 wOBA to 0.306. Giants are striking out at 24.1% over the window — something the opposing starter can lean on.

Season profile

Full Stats page →
MetricTwinsGiants
Record74-8465-93
Run differential / game (team quality)-0.40-0.53
Runs scored / game (offense, season)4.534.18
Runs allowed / game (defense, season, lower better)4.944.71
Season OPS0.7180.713
K% season (lower is better)21.2%21.8%
OPS vs opposing hand (season)0.6760.669

Season-long team quality, not recent form. Run differential and run environment come from the season standings; splits for all 30 teams live on the Stats page, including the run environment table.

Every team on today's slate, on any two axes you pick. Twins and Giants are highlighted.

Twins
Combined risk
5.3 Normal
Fatigue
5.7 Normal
Efficiency
5.9 Effective
Giants
Combined risk
7.7 Tired
Fatigue
7.0 Tired
Efficiency
3.7 Below average

Risk is what the model actually uses: fatigue blended with how well the pen has pitched. High fatigue with high efficiency is a tired pen that is still getting outs.

MetricTwinsGiants
Fatigue5.7/10, Normal7.0/10, Tired
Efficiency5.9/10, Effective3.7/10, Below average
Combined risk5.3/10, Normal7.7/10, Tired
Relief innings, last 7 days26.022.7
Back-to-back arms65
7-day ERA2.425.56
7-day WHIP1.381.63

Fatigue measures workload. Efficiency measures recent run prevention. Combined risk is what the moneyline and totals systems use.

Run total projection

Full Totals Projections →
Leo projection
7.0
Market total
5.5
Projected away runs
3.9
Projected home runs
3.4
Over price
+105
Under price
-122
Minnesota Twins team total
3.9 projected
Line 4.5 · O +102 / U -118
No team-total lean
San Francisco Giants team total
3.4 projected
Line 3.5 · O +105 / U -125
No team-total lean

The model projects 1.5 runs above the market total. A research lean still requires a setup rating of at least 7.0/10. Team totals remain research-only until their graded sample is established.

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