MLB matchup analysis

Cardinals vs Pirates Prediction, Odds and Model Pick

Wednesday, September 23, 2026 at PNC Park · 6:40 PM ET

Pass

Leo decision: Pass on Cardinals vs Pirates

Lab Rating
7.0/10
Model lean
Pirates 67.6%
Market probability
59.3%
Model edge
+8.3%
Best moneyline
-155
Sportsbooks checked
5
Leo model
67.6%
Market
59.3%

The case for Pittsburgh Pirates

Pitching plan edge: 9 points
Leo gives the Pittsburgh Pirates pitching plan the edge over Matthew Liberatore (9 points on Leo's pitcher score). Lake Bachar is projected for only 2 innings, with the Pittsburgh Pirates bullpen covering the rest -- this compares the Pittsburgh Pirates blended starting-pitcher-and-bullpen quality against Matthew Liberatore's own line, not two starters directly.
Bats are hot: +0.025 wOBA
Pittsburgh Pirates is outhitting its own season form over the last 15 days. Recent form is context, not a model input, but it points the same way here.

The case for St. Louis Cardinals

Late-inning bullpen advantage
Pittsburgh Pirates relievers have a 3.09 ERA over the last 7 days; St. Louis Cardinals relievers have a 3.43. Pittsburgh Pirates also have 7 arms pitching on back-to-back days, against 5 for St. Louis Cardinals. If this is still close after six innings, that gap favors St. Louis Cardinals.

Why it is not official

Setup quality below the bar
Lab Rating is 7.0/10, under the 7.2/10 required for an official pick.
Own bullpen carries risk: 7.6/10
The Pittsburgh Pirates bullpen comes in tired. A lead after six innings is less safe than usual.

Why the setup score is what it is

Conviction: 6.31/10
Leo's win probability for Pittsburgh Pirates (67.6%) is well clear of a coin flip -- this is a real, stated lean, not a guess.
Pitching plan: 16/40
Pittsburgh Pirates rates 70 on Leo's pitcher score, judged on its own merits (50-80 is the credited range). Average or below by that measure, so it earns little or none of the available credit here -- independent of who the opponent is throwing.
Offense: 47.67/50
Pittsburgh Pirates's recent offensive form clearly outpaces St. Louis Cardinals's over the tracked windows.

Why the price is what it is

Team strength: 54.1%
Before any pitcher or bullpen adjustment, Leo's team-strength model alone makes Pittsburgh Pirates 54.1% to win. Everything below moves the price from this starting point.
Pitcher score gap: 11 points
The pitcher-score gap favors Pittsburgh Pirates by 11 points. This is the biggest single mover of the price -- a large gap moves it a lot, a small gap barely moves it.
Bullpen adjustment: -0.063
The bullpen-fatigue gap between the two pens nudges the price toward St. Louis Cardinals. This moves the price less than the starting pitchers do, since a starter covers more of the game than the bullpen.
Net effect: 54.1% -> 67.6%
Team strength alone had Pittsburgh Pirates at 54.1%. After the pitcher and bullpen terms, the price is 67.6% -- the same number shown as Model Lean above.
The verdict Leo passes. This is a bullpen game -- no confirmed traditional starter, so Leo does not publish an official pick here.
Read the full model output

This is a bullpen game -- no confirmed traditional starter, so Leo does not publish an official pick here.

Final result

Cardinals 5, Pirates 1

How the analysis held up

St. Louis Cardinals won. Leo's model favored the other side.

Lake Bachar (Pittsburgh Pirates), the starter Leo's pitcher score favored, actually outpitched Matthew Liberatore: 1.2 IP, 0 ER (0.00 ERA) against 5.2 IP, 1 ER (1.59 ERA). The edge held up. Both starters were sharp; the edge is a narrow one between two good outings.

The St. Louis Cardinals bullpen was not flagged pregame, but it had a night worth noting: 0 earned runs allowed over 3.1 relief innings (0.00 ERA) — quietly better than the pregame read implied.

The Pittsburgh Pirates bullpen was flagged as elevated risk pregame (Tired). In relief it actually allowed 5 earned runs over 7.1 innings (6.14 ERA) — the risk read showed up.

St. Louis Cardinals scored 5, 1.5 more than the 3.5 pregame projection.

Pittsburgh Pirates scored 1, 3.4 fewer than the 4.4 pregame projection.

Likely driver: the St. Louis Cardinals bullpen quietly shut the game down (0.00 ERA over 3.1 innings), unflagged pregame, and the opposing starter (1.59 ERA) was sharp when the read expected an edge the other way.

Game information

MatchupSt. Louis Cardinals at Pittsburgh Pirates
DateWednesday, September 23, 2026
First pitch6:40 PM ET
VenuePNC Park
Starting pitchersMatthew Liberatore vs Lake Bachar
WeatherGame-time forecast: 60°F, 0% precipitation chance, 5 mph wind from E.

Starting pitcher matchup

Full Pitcher Matchup Tool →
Matthew LiberatoreCardinals · LHP
vs
Lake BacharPirates · RHP
MetricCardinalsPirates
Pitching planTraditional starterOpener / bullpen game
Expected innings52
ThrowsLR
Leo pitcher score (higher is better)5370
ERA (lower is better)5.233.49
WHIP (lower is better)1.471.14
K/9 (higher is better)8.99.4
K-BB% (higher is better)14.7%15.1%
K% (higher is better)22.8%25.3%
BB% (lower is better)8.2%10.2%
BB/9 (lower is better)3.23.8
HR/9 (lower is better)1.61.4
Ground-ball rate40.4%45.6%
Fly-ball rate59.6%54.4%

Pitching plan edge: Leo gives the Pittsburgh Pirates pitching plan the edge over Matthew Liberatore (9 points on Leo's pitcher score). Lake Bachar is projected for only 2 innings, with the Pittsburgh Pirates bullpen covering the rest -- this compares the Pittsburgh Pirates blended starting-pitcher-and-bullpen quality against Matthew Liberatore's own line, not two starters directly.

Blended read: For the Pittsburgh Pirates, the bullpen is projected to throw more of the game than Lake Bachar (about 2 innings for the starter), so Leo grades that side on a whole-game effective ERA of 4.37 rather than Lake Bachar's own 3.49. Whole-game, that is 4.37 for the Pittsburgh Pirates against 4.54 on the other side, so the blended read leans Pittsburgh Pirates.

How to read this: the scorecards above name the starters; every number lives in this table.

Strikeout Projections Full strikeout projections →

4.6 Leo projected Ks
No K play · +0.1K difference is below Leo's 0.7K threshold
Market 4.5K · O -142 / U +122 · 6 books
Lake Bachar strikeouts
2.3 Leo projected Ks
No strikeout line posted when this page was generated

Same data source as the Pitcher Matchup Tool, where every starter on the slate is compared side by side.

Cardinals are 4-6 in their last 10 and averaging 3.6 runs per game over the last 15 days; Pirates are 6-4 in their last 10 and averaging 4.3 runs per game over the last 15 days. Season run differential separates them by almost nothing (-0.13 against +0.17).

MetricCardinalsPirates
Last 104-66-4
Last 10 by venue (away team on the road, home team at home)4-6 on the road6-4 at home
OPS, last 15 days0.5890.797
wOBA, last 15 days (hot/cold read)0.2670.351
Runs per game, last 15 days3.64.3
K% last 15 days (lower is better)22.8%19.6%

Last 15 days only. Hot and cold streaks for all 30 teams live on the Stats page.

30-day offense

Full offense tool →
Last 30 daysCardinalsPirates
OPS0.676 (-0.019 vs szn)0.722 (-0.013 vs szn)
Runs per game4.77 (+0.304 vs szn)3.77 (-0.960 vs szn)
wOBA (model offense input)0.300 (-0.008 vs szn)0.322
K% (lower is better)22.8% (+1.8% vs szn)22.1% (-1.9% vs szn)

Over the last 30 days the Pirates have been the better offense, 0.322 wOBA to 0.300.

Season profile

Full Stats page →
MetricCardinalsPirates
Record76-8180-77
Run differential / game (team quality)-0.13+0.17
Runs scored / game (offense, season)4.494.75
Runs allowed / game (defense, season, lower better)4.624.58
Season OPS0.6940.736
K% season (lower is better)21.0%24.0%
OPS vs opposing hand (season)0.6870.700

Season-long team quality, not recent form. Run differential and run environment come from the season standings; splits for all 30 teams live on the Stats page, including the run environment table.

Every team on today's slate, on any two axes you pick. Cardinals and Pirates are highlighted.

Cardinals
Combined risk
5.5 Normal
Fatigue
5.8 Normal
Efficiency
5.6 Effective
Pirates
Combined risk
7.6 Tired
Fatigue
7.9 Tired
Efficiency
5.7 Effective

Risk is what the model actually uses: fatigue blended with how well the pen has pitched. High fatigue with high efficiency is a tired pen that is still getting outs.

MetricCardinalsPirates
Fatigue5.8/10, Normal7.9/10, Tired
Efficiency5.6/10, Effective5.7/10, Effective
Combined risk5.5/10, Normal7.6/10, Tired
Relief innings, last 7 days21.032.0
Back-to-back arms57
7-day ERA3.433.09
7-day WHIP1.241.28

Fatigue measures workload. Efficiency measures recent run prevention. Combined risk is what the moneyline and totals systems use.

Run total projection

Full Totals Projections →
Leo projection
7.8
Market total
7.0
Projected away runs
3.6
Projected home runs
4.3
Over price
+100
Under price
-113
St. Louis Cardinals team total
3.6 projected
Line 3.5 · O +105 / U -125
No team-total lean
Pittsburgh Pirates team total
4.3 projected
Line 3.5 · O -114 / U -102
Over research lean (+0.8)

The model projects 0.8 runs above the market total. A research lean still requires a setup rating of at least 7.0/10. Team totals remain research-only until their graded sample is established.

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Model outputs are not guarantees. Leo provides analysis and education only. Every official pick remains visible on the Results page. 21+. If you or someone you know has a gambling problem, call 1-800-GAMBLER.