MLB matchup analysis

Cardinals vs Pirates Prediction, Odds and Model Pick

Thursday, September 24, 2026 at PNC Park · 12:35 PM ET

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Leo prediction: Pittsburgh Pirates moneyline

Lab Rating
7.2/10
Model lean
Pirates 59.2%
Market probability
57.3%
Model edge
+1.9%
Best moneyline
-140
Sportsbooks checked
6
Leo model
59.2%
Market
57.3%

The case for Pittsburgh Pirates

Why Leo leans Pittsburgh Pirates
Leo's model makes Pittsburgh Pirates 59.2% to win. No single factor dominates — the starting pitcher matchup, recent bats tilt the same way, enough to lean Pittsburgh Pirates even though it does not clear the bar for a high-confidence pick.

The case for St. Louis Cardinals

Late-inning bullpen advantage
Pittsburgh Pirates relievers have a 3.41 ERA over the last 7 days; St. Louis Cardinals relievers have a 2.66. Pittsburgh Pirates also have 7 arms pitching on back-to-back days, against 5 for St. Louis Cardinals. If this is still close after six innings, that gap favors St. Louis Cardinals.

Why it is not official

Below the 61.0% official gate
Win probability is 59.2%. Leo does not make a game official below 61.0%, no matter how good the price is. This is a value spot, not a high-confidence winner.
Own bullpen carries risk: 9.3/10
The Pittsburgh Pirates bullpen comes in high risk. A lead after six innings is less safe than usual.

Why the setup score is what it is

Conviction: 2.1/10
Leo leans toward Pittsburgh Pirates, but not strongly enough to earn full conviction credit.
Pitching plan: 28/40
Paul Skenes rates 71 on Leo's pitcher score, judged on its own merits (50-80 is the credited range). That is a strong start on its own, and it earns most or all of the available credit here.
Offense: 41.69/50
Pittsburgh Pirates's recent offensive form clearly outpaces St. Louis Cardinals's over the tracked windows.

Why the price is what it is

Team strength: 53.8%
Before any pitcher or bullpen adjustment, Leo's team-strength model alone makes Pittsburgh Pirates 53.8% to win. Everything below moves the price from this starting point.
Pitcher score gap: 5 points
The pitcher-score gap favors Pittsburgh Pirates by 5 points. This is the biggest single mover of the price -- a large gap moves it a lot, a small gap barely moves it.
Bullpen adjustment: -0.132
The bullpen-fatigue gap between the two pens nudges the price toward St. Louis Cardinals. This moves the price less than the starting pitchers do, since a starter covers more of the game than the bullpen.
Net effect: 53.8% -> 59.2%
Team strength alone had Pittsburgh Pirates at 53.8%. After the pitcher and bullpen terms, the price is 59.2% -- the same number shown as Model Lean above.
The verdict Worth monitoring, nothing more. The setup has pieces but does not add up to a bet at today's price.
Read the full model output

Pittsburgh Pirates remains on the watchlist. Lab Rating 7.2/10: conviction 2.1, pitching plan 28, offense 41.69. Leo projects 59.2% against a 57.3% no-vig market number, a 1.9% model edge at -140. Pittsburgh Pirates owns the starting pitcher edge by 5 points. Bullpen read: Adds caution. Pittsburgh Pirates's pen efficiency: Average (5.4/10). Bullpen fatigue moved this probability down 12.0 points from 71.2% (starting pitcher and team strength only) to 59.2%. Lineup check: Pittsburgh Pirates is near its season form (+0.009 OPS); St. Louis Cardinals is in a cold stretch (-0.087 OPS). Recent form supports this side and is included in the unified run projection.

Final result

Cardinals 1, Pirates 2

How the analysis held up

Pittsburgh Pirates won, the side Leo's model favored.

Paul Skenes (Pittsburgh Pirates), the starter Leo's pitcher score favored, actually outpitched Kyle Leahy: 6.1 IP, 1 ER (1.42 ERA) against 2.0 IP, 1 ER (4.50 ERA). The edge held up.

The St. Louis Cardinals bullpen was not flagged pregame, but it had a night worth noting: 0 earned runs allowed over 6.0 relief innings (0.00 ERA) — quietly better than the pregame read implied. Note: 1 of the runs charged to the St. Louis Cardinals pitching staff overall was unearned — not something the bullpen's stuff should be blamed for.

The Pittsburgh Pirates bullpen was flagged as elevated risk pregame (High risk). In relief it actually allowed 0 earned runs over 2.2 innings (0.00 ERA) — the risk read did not show up on the scoreboard tonight.

Game information

MatchupSt. Louis Cardinals at Pittsburgh Pirates
DateThursday, September 24, 2026
First pitch12:35 PM ET
VenuePNC Park
Starting pitchersKyle Leahy vs Paul Skenes
WeatherGame-time forecast: 58°F, 0% precipitation chance, 4 mph wind from NE.

Starting pitcher matchup

Full Pitcher Matchup Tool →
Kyle LeahyCardinals · RHP
vs
Paul SkenesPirates · RHP
MetricCardinalsPirates
Pitching planTraditional starterTraditional starter
Expected innings4⅔5⅓
ThrowsRR
Leo pitcher score (higher is better)6671
ERA (lower is better)3.663.82
WHIP (lower is better)1.341.12
K/9 (higher is better)8.510.3
K-BB% (higher is better)15.3%21.2%
K% (higher is better)22.1%28.1%
BB% (lower is better)6.9%6.9%
BB/9 (lower is better)2.62.5
HR/9 (lower is better)1.01.0
Ground-ball rate53.7%44.6%
Fly-ball rate46.3%55.4%

Pitcher edge: Leo gives Paul Skenes a 5-point edge over Kyle Leahy, driven mainly by K-BB% (21.2% vs 15.3%) and K/9 (10.3 vs 8.5).

How to read this: the scorecards above name the starters; every number lives in this table.

Strikeout Projections Full strikeout projections →

Kyle Leahy strikeouts
4.7 Leo projected Ks
No strikeout line posted when this page was generated
Paul Skenes strikeouts
5.8 Leo projected Ks
No strikeout line posted when this page was generated

Same data source as the Pitcher Matchup Tool, where every starter on the slate is compared side by side.

Cardinals are 4-6 in their last 10 and averaging 3.7 runs per game over the last 15 days; Pirates are 6-4 in their last 10 and averaging 3.5 runs per game over the last 15 days. Season run differential separates them by almost nothing (-0.14 against +0.18).

MetricCardinalsPirates
Last 104-66-4
Last 10 by venue (away team on the road, home team at home)3-7 on the road7-3 at home
OPS, last 15 days0.6070.744
wOBA, last 15 days (hot/cold read)0.2740.330
Runs per game, last 15 days3.73.5
K% last 15 days (lower is better)25.1%20.9%

Last 15 days only. Hot and cold streaks for all 30 teams live on the Stats page.

30-day offense

Full offense tool →
Last 30 daysCardinalsPirates
OPS0.671 (-0.022 vs szn)0.725 (-0.010 vs szn)
Runs per game4.63 (+0.164 vs szn)3.73 (-1.005 vs szn)
wOBA (model offense input)0.298 (-0.010 vs szn)0.323
K% (lower is better)23.4% (+2.3% vs szn)21.7% (-2.3% vs szn)

Over the last 30 days the Pirates have been the better offense, 0.323 wOBA to 0.298.

Season profile

Full Stats page →
MetricCardinalsPirates
Record77-8180-78
Run differential / game (team quality)-0.14+0.18
Runs scored / game (offense, season)4.474.74
Runs allowed / game (defense, season, lower better)4.604.56
Season OPS0.6940.735
K% season (lower is better)21.0%24.0%
OPS vs opposing hand (season)0.6880.752

Season-long team quality, not recent form. Run differential and run environment come from the season standings; splits for all 30 teams live on the Stats page, including the run environment table.

Every team on today's slate, on any two axes you pick. Cardinals and Pirates are highlighted.

Cardinals
Combined risk
4.9 Normal
Fatigue
5.6 Normal
Efficiency
6.5 Effective
Pirates
Combined risk
9.3 High risk
Fatigue
9.5 High risk
Efficiency
5.4 Average

Risk is what the model actually uses: fatigue blended with how well the pen has pitched. High fatigue with high efficiency is a tired pen that is still getting outs.

MetricCardinalsPirates
Fatigue5.6/10, Normal9.5/10, High risk
Efficiency6.5/10, Effective5.4/10, Average
Combined risk4.9/10, Normal9.3/10, High risk
Relief innings, last 7 days20.337.0
Back-to-back arms57
7-day ERA2.663.41
7-day WHIP0.931.35

Fatigue measures workload. Efficiency measures recent run prevention. Combined risk is what the moneyline and totals systems use.

Run total projection

Full Totals Projections →
Leo projection
7.0
Market total
3.5
Projected away runs
3.6
Projected home runs
3.7
Over price
-131
Under price
+118
St. Louis Cardinals team total
3.6 projected
Line 1.5 · O -150 / U +140
Over research lean (+2.1)
Pittsburgh Pirates team total
3.7 projected
Line 2.5 · O +200 / U -185
Over research lean (+1.2)

The model projects 3.5 runs above the market total. A research lean still requires a setup rating of at least 7.0/10. Team totals remain research-only until their graded sample is established.

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