NFL teams · NFC West · 2026 season

San Francisco 49ers predictions 2026

The 49ers went 5-1 in the 6 games Leo analyzed between September 20 and October 25. The side Leo favored won 5 of 6 of those games. When Leo favored the 49ers, they went 5-1.

5-1
49ers record in games Leo analyzed
5-1
Leo’s reads on 49ers games (right‑wrong)
72%
Leo’s average win chance for the 49ers

Every 49ers game

DateOpponentLeo’s chance (49ers)Leo favoredFinal score49ers resultLeo’s read
Oct 25 Wk 7at Falcons63%49ers49ers 20, Falcons 29LostWrong
Oct 19 Wk 6vs Commanders77%49ers49ers 23, Commanders 17WonRight
Oct 11 Wk 5at Seahawks54%49ers49ers 32, Seahawks 29WonRight
Oct 4 Wk 4vs Broncos76%49ers49ers 24, Broncos 14WonRight
Sep 27 Wk 3vs Cardinals78%49ers49ers 36, Cardinals 30WonRight
Sep 20 Wk 2vs Dolphins84%49ers49ers 35, Dolphins 13WonRight

Opponents link to Leo’s full game analysis: spread, total, quarterbacks and touchdown scorer chances.

More from the NFC West

Arizona Cardinals · Los Angeles Rams · Seattle Seahawks

See all 32 teams, this week’s NFL predictions, every NFL game page and Leo’s NFL record.

For entertainment and informational purposes. Leo’s win chances are information, not betting advice, and no model can promise outcomes. 21+. If gambling stops being fun, call 1-800-MY-RESET.